You must separate multiple addresses in the headers of the mail buffer
with commas. This is because Emacs supports RFC822 standard addresses
like this one:
To: Willy Smith <wks@xpnsv.lwyrs.com>
However, you do not need to separate addresses with commas in your
.mailrc file.
WARNING: Emacs breaks up aliases in the .mailrc file into multiple
addresses both on commas and on whitespace, regardless of any use of
quotes. This is probably a bug. You can get around this by directly
setting the value of mail-aliases.